
Alcohol allergies are extremely rare, and true allergic reactions are often confused with alcohol intolerance. However, an alcohol allergy can be life-threatening and cause anaphylaxis. If you have an alcohol allergy, it is recommended that you carry an EpiPen (epinephrine injection) at all times. EpiPens deliver a dose of epinephrine, also known as adrenaline, to counteract the allergic reaction and buy you time to get to the hospital. EpiPens are prescribed for emergency allergic reactions and are safe to use even if you have been drinking alcohol.
| Characteristics | Values |
|---|---|
| Allergic reaction to alcohol | Rare |
| Alcohol allergy symptoms | Mild: itchy mouth or eyes; Severe: vomiting, anaphylaxis, weak pulse, nausea, swelling, trouble breathing |
| Treatment for mild allergic reaction | Over-the-counter oral antihistamines |
| Treatment for severe allergic reaction | Epinephrine (adrenaline) shots, also known as EpiPen |
| Alcohol intolerance | More common than alcohol allergy |
| Alcohol intolerance symptoms | Uncomfortable |
| Treatment for alcohol intolerance | Limit or avoid certain types of alcohol; Over-the-counter or prescribed medications |
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What You'll Learn

Alcohol allergy vs. intolerance
Alcohol allergy and alcohol intolerance are two different conditions. An alcohol allergy is a rare toxic reaction to alcohol that can be fatal. In this case, the immune system overreacts to alcohol, treating it as a harmful intruder and producing antibodies to fight it off. This causes an allergic reaction.
If you have a true alcohol allergy, you should avoid drinking alcohol entirely. Even small amounts of alcohol can cause symptoms, including anaphylaxis, a severe reaction that can include a rapid, weak pulse, nausea, and vomiting. If you have an alcohol allergy, you should carry epinephrine shots (e.g. EpiPen) with you at all times and wear a medical ID bracelet.
On the other hand, alcohol intolerance is a genetic, metabolic disorder of the digestive system. It occurs when the body cannot properly break down alcohol or the toxins in alcohol, leading to uncomfortable symptoms. Alcohol intolerance can be caused by a deficiency in the enzyme aldehyde dehydrogenase (ALDH2), which is responsible for breaking down acetaldehyde, a metabolite of alcohol, into acetate, a non-toxic substance. People with alcohol intolerance may still consume alcohol, but they will likely experience side effects. Treatment options for alcohol intolerance include lifestyle changes such as limiting alcohol intake, choosing drinks low in sulfites and other preservatives, staying hydrated, and eating before consuming alcohol.
It is important to note that the symptoms of alcohol allergy and alcohol intolerance may overlap, and it is easy to confuse the two conditions. If you experience symptoms after drinking alcohol, it is recommended to consult a healthcare professional for further advice and testing.
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Symptoms of an allergic reaction
An allergic reaction to alcohol is rare, but it can be life-threatening. Symptoms of an allergic reaction to alcohol may include:
- Skin itching, which may result in redness or a rash. The skin may feel agitated and tender to the touch.
- Raised, itchy, and red patches on the skin that may vary in size and shape. These can be localised or widespread.
- Itchiness or puffiness, especially around the eyes, mouth, and nose.
- A rash, dermatitis, or skin irritation.
- Breathing difficulties such as shortness of breath. Symptoms may include a tight chest or a whistling sound during breathing, often linked to narrowed air passages.
- Anaphylaxis, a severe and potentially life-threatening allergic reaction that necessitates immediate medical intervention. Symptoms include a rash, low pulse, nausea, vomiting, swelling, trouble breathing, and shock.
It is important to note that an allergic reaction to alcohol can occur even after exposure to tiny amounts of alcohol. If you suspect an allergy to alcohol, consult a medical professional for a precise diagnosis and management plan.
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When to use an EpiPen
An EpiPen is a brand name for epinephrine auto-injectors. It is a preloaded syringe that delivers epinephrine, also known as adrenaline. An EpiPen is used to treat severe allergic reactions, also known as anaphylaxis. Anaphylaxis is a potentially life-threatening allergic reaction that can cause a range of symptoms, including a rash, low pulse, nausea, vomiting, swelling, and trouble breathing. In the event of anaphylaxis, it is important to use an EpiPen immediately and seek emergency medical attention. The epinephrine from the pen may last 30 minutes to a couple of hours, which should be enough time to get to a hospital.
If you have a known allergy, it is important to carry an EpiPen with you at all times and to keep one in places where you spend the most time, such as at home, work, or school. It is also important to wear a medical ID bracelet that alerts others of your allergy.
In the case of a mild allergic reaction to alcohol or other allergens, over-the-counter oral antihistamines may be enough to treat the symptoms. However, if you experience any signs of a severe reaction, such as anaphylaxis, you should use an EpiPen immediately and then go to the nearest emergency department for follow-up care. It is important to note that an EpiPen will not replace a visit to the emergency room, but it buys you time to get to the hospital.
It is worth noting that true alcohol allergy is rare, and most people who have a reaction to alcohol have an intolerance. Alcohol intolerance is a genetic condition where the digestive system cannot properly break down alcohol. Symptoms of alcohol intolerance can include mild discomfort to more severe pain. If you experience severe pain after drinking alcohol, it is important to see a doctor as it could be a sign of a more serious disorder.
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How to use an EpiPen
Alcohol allergy is rare, and most people who react to alcohol have an intolerance. However, if you have a true alcohol allergy, even small amounts of alcohol can cause symptoms, and in some cases, it can cause anaphylaxis. If you have been prescribed an EpiPen, you should carry it with you at all times. Here is how to use an EpiPen:
Firstly, you should familiarise yourself with the steps required to administer your EpiPen. You can watch a demonstration video, and you can also order an EpiPen Trainer to practice the steps with your friends and family. You should also check your EpiPen regularly to make sure the solution is clear and colourless. If the solution is discoloured or contains particles, it will need to be replaced.
To administer the EpiPen, there is no need to remove clothing, but make sure the orange end will not hit buckles, zips, buttons, or thick seams on your clothes. Grasp the EpiPen in your dominant hand and remove the blue safety cap by pulling straight up. Remember, blue to the sky, orange to the thigh! Hold the EpiPen at 90 degrees, approximately 10cm away, with the orange tip pointing towards your outer thigh. Jab the EpiPen firmly into your outer thigh at a right angle. Hold firmly for 3 seconds, before removing and safely discarding.
After administering the EpiPen, dial for an ambulance and say "anaphylaxis".
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Where to keep your EpiPen
If you have been prescribed an EpiPen, it is important to keep it with you at all times and ensure it is easily accessible in case of an emergency. Here are some guidelines on where to keep your EpiPen:
At Home
It is recommended to store your EpiPen in a safe place that is easily accessible in case of an emergency. You can purchase a separate EpiPen for your home and keep it in a designated location, such as a drawer or cabinet. Remember to store it at room temperature, typically between 15°C and 25°C, and avoid exposing it to extreme temperatures or direct sunlight. Regularly check the expiration date and inspect the solution for any discoloration or particles.
On the Go
When carrying your EpiPen with you, it is important to keep it protected and at the appropriate temperature. Consider investing in an insulated medical carrying case to maintain room temperature, especially if you plan to be outdoors for extended periods in hot or cold weather. Always carry your EpiPen with you, whether in your bag or a specially designed carrier tube, and ensure it is easily accessible in case of an emergency.
At School or Work
If you or your child needs an EpiPen at school, consider purchasing a separate device for storage at school. Consult with the school administration about safe storage options, such as the nurse's office or a designated storage area. Similarly, if you need an EpiPen at work, discuss safe storage options with your employer to ensure easy access in an emergency.
During Travel
When travelling, it is crucial to have your EpiPen with you at all times. Keep it in your carry-on luggage or personal item to ensure it remains within reach. Remember to follow the storage guidelines, especially when travelling to hot or cold destinations, and consider using an insulated case to maintain the appropriate temperature.
In Vehicles
It is generally not recommended to store EpiPens in vehicles due to extreme temperature fluctuations. However, if you must keep an EpiPen in your vehicle, take precautions to maintain a stable temperature. Do not leave it in direct sunlight or in the glove compartment, and consider using an insulated case. Regularly check the EpiPen for any signs of degradation due to temperature changes.
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Frequently asked questions
An allergic reaction to alcohol occurs when a person's immune system overreacts to alcohol exposure, treating it as a threat. The body produces antibodies, and when they come into contact with alcohol, they trigger an allergic reaction.
True alcohol allergies are very rare. Most people who have a reaction to alcohol have an intolerance, which is more common.
Symptoms of an alcohol allergy can range from mild, such as an itchy mouth or eyes, to severe, including vomiting or anaphylaxis. Anaphylaxis is a potentially life-threatening allergic reaction that can cause a rash, low pulse, and shock.
If you have a true alcohol allergy, you should carry an Epipen with you at all times. An Epipen delivers epinephrine, also known as adrenaline, and is used to treat severe allergic reactions. If you experience an allergic reaction, you should use the Epipen and then go to your nearest emergency department for follow-up care.
If you have an alcohol allergy, you should avoid drinking alcohol entirely. You should also wear a medical ID bracelet that informs health professionals of your allergy.











































