
Smoking and alcohol consumption are two of the leading preventable causes of death worldwide. Tobacco smoking has been one of the world's largest health problems for decades, killing around 100 million people in the 20th century. In the United States, cigarette smoking causes about one in every five deaths annually, with around 480,000 deaths attributed to smoking each year, including 41,000 from secondhand smoke. Globally, about a quarter of cancer deaths are attributed to smoking. Alcohol-related deaths have also been on the rise in the US, with liver disease deaths doubling over the course of 20 years, and alcohol-linked cancer deaths showing a similar increase.
| Characteristics | Values |
|---|---|
| Number of deaths attributed to tobacco | 7-8 million |
| Number of deaths attributed to second-hand smoke | 1.3 million |
| Number of deaths attributed to chewing tobacco | 56,000 |
| Number of deaths caused by tobacco in the US | 490,000+ |
| Number of deaths caused by tobacco in the US (including second-hand smoke) | 480,000+ |
| Number of deaths caused by tobacco among men in the US (including second-hand smoke) | 278,544 |
| Number of deaths caused by tobacco among women in the US (including second-hand smoke) | 201,773 |
| Number of deaths caused by second-hand smoke in the US | 41,000 |
| Number of deaths caused by second-hand smoke from lung cancer in the US | 7,333 |
| Number of deaths caused by second-hand smoke from heart disease in the US | 33,951 |
| Percentage of deaths from cancer attributed to smoking globally | 25% |
| Percentage of deaths from cancer attributed to smoking in richer countries | >25% |
| Percentage of deaths from cancer attributed to smoking in poorer countries | <25% |
| Percentage of premature deaths attributed to second-hand smoke across the world | varies |
| Highest death rates from tobacco smoking | Asia and Eastern Europe |
| Lowest death rates from tobacco smoking | Lowest-income countries |
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What You'll Learn

Smoking and alcohol cause 490,000+ deaths in the US each year
The annual death toll from tobacco in the US is over 490,000 lives, including deaths from second-hand smoke. This figure is more than the number of deaths from AIDS, alcohol, car accidents, illegal drugs, murders, and suicides combined. Tobacco kills more than 8 million people globally each year, with 7 million of those deaths resulting from direct tobacco use and 1.3 million from second-hand smoke exposure. The problem is most severe in low- and middle-income countries, where 80% of the world's 1.3 billion tobacco users reside.
Smoking is a major risk factor for several leading causes of death, including lung cancer, heart disease, and respiratory diseases. It is the most common form of tobacco use, although other products such as waterpipe tobacco, cigars, cigarillos, heated tobacco, and smokeless tobacco products are also harmful and can cause cancer. Quitting smoking before the age of 40 reduces the risk of dying from a smoking-related disease by about 90%.
The economic costs of tobacco use are substantial, with healthcare costs and lost productivity in the US alone totalling over $500 billion annually. Additionally, there are other non-healthcare costs, such as residential and commercial property losses from smoking-caused fires, tobacco-related cleaning and maintenance, and social security payments for children who have lost parents to smoking-caused deaths. The tobacco industry spends billions of dollars on marketing its products, and it has been proven that tobacco is addictive and causes disease and death.
While enormous progress has been made in reducing smoking rates, tobacco use continues to exact a terrible toll on individuals, families, businesses, and governments. It shortens the lives of its users and imposes a significant economic burden on society.
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Tobacco is the leading cause of preventable death in the US
Tobacco use is the leading cause of preventable death in the United States, causing more than 490,000 deaths each year. This figure includes deaths from second-hand smoke, which claims the lives of an estimated 41,000 Americans annually. Tobacco kills more people than alcohol, AIDS, car accidents, illegal drugs, murders, and suicides combined. It is a major public health threat, with cigarette smoking being the most common form of tobacco consumption.
The harmful effects of tobacco are well-documented. All forms of tobacco use are harmful, and there is no safe level of exposure. It is a proven cause of cancer, with smokeless tobacco also known to increase the risk of sudden death from ventricular arrhythmias. Smoking increases the risk of dying from various types of cancer, including lung, tracheal, and bronchus cancer. It also significantly raises the likelihood of mortality from respiratory diseases, heart disease, bronchitis, and emphysema. The impact of tobacco on the heart is particularly concerning, with smoking increasing the risk of death from coronary heart disease by almost four to five times, depending on the age group.
The consequences of tobacco use extend beyond health issues. Tobacco use contributes to poverty by diverting household spending away from essential needs such as food and shelter. The economic costs associated with tobacco are substantial, including healthcare expenditures and lost productivity. In the United States alone, tobacco costs over $241 billion in healthcare expenses and more than $365 billion in lost productivity annually. Additionally, there are non-healthcare costs, such as residential and commercial property losses from smoking-caused fires, tobacco-related cleaning and maintenance, and expenditures through Social Security Survivors Insurance for children who have lost a parent to tobacco-caused death.
The tobacco epidemic is not limited to the United States but is a global issue. Worldwide, tobacco kills more than 8 million people annually, with more than 7 million deaths resulting from direct tobacco use and around 1.3 million from exposure to second-hand smoke. The burden of tobacco-related illness and death falls disproportionately on low- and middle-income countries, where around 80% of the world's 1.3 billion tobacco users reside. The high addiction potential of tobacco makes it challenging for users to curb their spending on it, further exacerbating the economic impact.
Addressing the tobacco epidemic is crucial to reducing its devastating impact on public health and economies worldwide. Efforts to reduce tobacco consumption, such as the WHO Framework Convention on Tobacco Control, have been implemented, and it is important to continue advocating for tobacco-free lifestyles, especially among youth, to prevent the onset of tobacco use and its detrimental consequences.
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Globally, 8 million people die from tobacco use annually
Smoking is one of the world's biggest public health threats, killing about 8 million people each year globally. Tobacco use is the leading cause of preventable death in the United States, with more than 490,000 deaths annually, including those from second-hand smoke. This figure is higher than the number of deaths from AIDS, alcohol, car accidents, illegal drugs, murders, and suicides combined.
The health burdens of smoking are shifting from high-income to low- and middle-income countries, where the majority of the world's 1.3 billion tobacco users reside. In these countries, the burden of tobacco-related illness and death is heaviest, with around 80% of users living in such nations. Tobacco use contributes to poverty by diverting household spending away from essential needs such as food and shelter. The economic costs of tobacco use are substantial, including significant healthcare costs for treating tobacco-related diseases and lost human capital due to tobacco-attributable morbidity and mortality.
Cigarette smoking is the most common form of tobacco use globally, with other products including waterpipe tobacco, cigars, cigarillos, heated tobacco, roll-your-own tobacco, pipe tobacco, bidis, kreteks, and smokeless tobacco. Smokeless tobacco, including nicotine pouches, is a known cause of cancer, and the nicotine in these products may increase the risk of sudden death from ventricular arrhythmias. While heated tobacco products (HTPs) claim to reduce risk, there is no evidence to support this, as they still contain toxicants, some of which are not found in conventional tobacco smoke.
The World Health Organization (WHO) has adopted the WHO Framework Convention on Tobacco Control (WHO FCTC) to address the tobacco epidemic, with 182 countries currently parties to this treaty. Despite enormous progress in reducing smoking rates, tobacco use remains a significant problem, imposing a heavy toll on families, businesses, and governments.
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1.3 million non-smokers die from second-hand smoke exposure
Smoking and alcohol are two of the most common causes of preventable death worldwide. Tobacco use, in particular, is the leading cause of preventable death in the United States, killing more than 490,000 people annually. This figure includes deaths from second-hand smoke exposure, with an estimated 41,000 deaths attributed to passive smoking in the US alone. Globally, the number of non-smokers dying from second-hand smoke exposure is estimated to be around 1.3 million.
Second-hand smoke, also known as passive smoking, occurs when non-smokers inhale smoke from smokers. This smoke contains over 7,000 chemicals, including hundreds that are toxic and about 70 that can cause cancer. Even brief exposure to second-hand smoke can be harmful to one's health, and prolonged exposure significantly increases the risk of developing various diseases, including cancer and heart disease.
The World Health Organization (WHO) has recognized the tobacco epidemic as one of the biggest public health threats in history, killing over 8 million people worldwide each year. While the majority of these deaths are a result of direct tobacco use, the estimated 1.3 million deaths from second-hand smoke exposure highlight the serious impact of passive smoking on global health. This issue is particularly prevalent in low- and middle-income countries, where around 80% of the world's 1.3 billion tobacco users reside.
The economic costs of tobacco use, including passive smoking, are also substantial. In the United States, tobacco costs the country over $241 billion in healthcare expenditures and more than $365 billion in lost productivity annually. Additionally, tobacco use contributes to poverty, especially in low- and middle-income countries, by diverting household spending away from basic needs such as food and shelter towards tobacco products.
Reducing exposure to second-hand smoke is crucial to decreasing the number of non-smoker deaths attributed to passive smoking. Implementing smoke-free policies in public places and workplaces, increasing tobacco taxes, and offering support and education to smokers seeking to quit can all help reduce the harmful impact of second-hand smoke exposure.
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Smoking causes 25% of cancer deaths globally
Smoking is the leading cause of preventable death in the United States, and it imposes a terrible toll on families, businesses, and the government. Tobacco kills more than 490,000 people annually in the US—more than AIDS, alcohol, car accidents, illegal drugs, murders, and suicides combined. The economic costs of tobacco use are also substantial, with healthcare expenditures exceeding $241 billion and lost productivity costing over $365 billion annually.
On a global scale, tobacco use is responsible for about 2.6 million cancer deaths each year, according to data from 2019. This accounts for 25% of all cancer deaths worldwide, making it the largest avoidable cause of cancer deaths. Tobacco use contributes to 14 types of cancer, with lung cancer being the primary consequence. Almost 7 out of 10 lung cancer deaths are caused by tobacco use, and it remains the leading cause of death among men and women for this type of cancer.
The harmful effects of tobacco extend beyond lung cancer, impacting nearly every part of the body. Tobacco use has been linked to cancers of the larynx, oral cavity, pharynx, oesophagus, pancreas, bladder, stomach, colon and rectum, liver, cervix, and kidney, as well as acute myeloid leukemia (AML). Quitting smoking is crucial for lowering the risk of these cancers. Within 5 to 10 years of quitting, the chances of developing cancer in the mouth, throat, or voice box drop by half.
The World Health Organization (WHO) has addressed the tobacco epidemic by adopting the WHO Framework Convention on Tobacco Control (WHO FCTC) in 2003. This treaty now has 182 member countries working to save lives and reduce healthcare costs. Despite these efforts, tobacco remains a significant public health threat, killing over 8 million people annually worldwide. More than 7 million of these deaths are attributed to direct tobacco use, while around 1.3 million are due to exposure to second-hand smoke.
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