
Equate Daytime Cold and Flu is an over-the-counter medication manufactured by Wal-Mart Stores Inc. that provides relief from common cold and flu symptoms such as nasal congestion, cough, sore throat, headache, and fever. Its active ingredients include acetaminophen, dextromethorphan HBr, and phenylephrine HCl. The daytime formula is alcohol-free and antihistamine-free. However, the Equate Nighttime Cold and Flu formula does contain 10% alcohol in addition to acetaminophen, dextromethorphan HBr, and doxylamine succinate. It is important to note that consuming alcohol while taking any medication for colds or flu is generally not recommended as it can lead to dehydration, worsen symptoms, and have dangerous interactions with certain ingredients.
| Characteristics | Values |
|---|---|
| Alcohol Content | Equate Nighttime Cold and Flu contains 10% alcohol. Equate Daytime Cold and Flu is alcohol-free. |
| Liver Warning | Both products contain acetaminophen. Severe liver damage may occur if more than 4,000 mg of acetaminophen is consumed in 24 hours. |
| Allergy Alert | Acetaminophen may cause severe skin reactions. |
| Sore Throat Warning | If the sore throat is severe, lasts for more than 2 days, or is accompanied by fever, headache, rash, nausea, or vomiting, consult a doctor promptly. |
| Drug Interactions | Do not consume with other drugs containing acetaminophen or monoamine oxidase inhibitors (MAOIs). |
| Side Effects | May cause dizziness, drowsiness, and increased risk of respiratory depression. |
| Drug-Drug Interactions | Alcohol can have dangerous interactions with cold and flu medication, exacerbating symptoms such as nausea, vomiting, and headaches. |
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What You'll Learn

Equate Daytime Cold and Flu is alcohol-free
It is important to note that severe liver damage may occur if an adult takes more than 4,000 mg of acetaminophen in 24 hours, or if the medication is taken with three or more alcoholic drinks per day. Equate Daytime Cold and Flu is a safe option for those looking to avoid alcohol in their cold and flu medication.
In contrast, Equate Nighttime Cold and Flu does contain alcohol. The active ingredients are similar to those in Equate Daytime Cold and Flu, but the nighttime version also includes Doxylamine Succinate to aid with sneezing and a runny nose. The alcohol content is listed as 10% in a 12 FL OZ (355 mL) bottle.
It is generally advised to avoid alcohol when taking any kind of medication for colds, flu, pain relief, or sleep aids. Alcohol can increase side effects and the risk of liver damage or other serious health issues. It can also impair the immune system, making it harder to recover from an illness. Certain medications, like cough suppressants and antihistamines, can have severe side effects when combined with alcohol, including increased dizziness and drowsiness.
Therefore, while Equate Daytime Cold and Flu is alcohol-free, it is important to be aware of the potential risks associated with consuming alcohol while taking any cold or flu medication.
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Equate Nighttime Cold and Flu contains 10% alcohol
It is imperative to note that the Equate Daytime Cold and Flu medication is alcohol-free. However, its nighttime counterpart, Equate Nighttime Cold and Flu, contains 10% alcohol. This distinction is crucial as consuming alcohol while taking certain medications can lead to adverse health effects.
Equate Nighttime Cold and Flu is a medication designed to provide relief from common cold and flu symptoms, including aches, fever, cough, and a runny nose. The active ingredients in this medication are acetaminophen, dextromethorphan HBr, and doxylamine succinate. It is available in a 12 FL OZ (355 mL) bottle, which contains 10% alcohol as listed in its ingredients.
The presence of alcohol in Equate Nighttime Cold and Flu is important to note due to the potential risks associated with mixing alcohol and medications. While taking any medication, including those for colds and flu, it is generally advised to refrain from consuming alcohol. This is because alcohol can exacerbate certain symptoms and impair the immune system, hindering the recovery process.
Additionally, specific medications may interact dangerously with alcohol. For instance, cough suppressants and antihistamines can lead to increased dizziness, drowsiness, and the risk of respiratory depression when combined with alcohol. Therefore, it is crucial to heed the warnings and ingredient lists on medications such as Equate Nighttime Cold and Flu to ensure safe and effective use.
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Mixing alcohol with cold and flu medication can cause dehydration
The Equate Daytime Cold and Flu medication is alcohol-free. However, the Equate Nighttime Cold and Flu medication contains 10% alcohol.
The risk of liver damage and depressed nervous system functioning increases with higher doses of medication and greater alcohol intake. Alcohol can also decrease the likelihood of experiencing relief from allergy, cold, and flu medications while increasing the likelihood of adverse effects and overdose. Mixing alcohol with medication can also lead to falls and serious injuries, especially among older people.
Women are more susceptible to alcohol-related damage to organs such as the liver due to their bodies generally having less water than men's bodies. Aging slows the body's ability to break down alcohol, so it remains in an individual's system longer, increasing the chance of adverse medication interactions.
It is advised to avoid alcohol when taking any kind of medication for colds, flu, pain relief, or sleep aids, and to always read medication labels and warnings.
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Alcohol and medication can cause dizziness and drowsiness
Equate Daytime Cold and Flu capsules are alcohol-free. However, Equate Nighttime Cold and Flu, which contains acetaminophen, dextromethorphan hydrobromide, and doxylamine succinate, has 10% alcohol.
Alcohol and medication can have dangerous interactions, causing dizziness and drowsiness. Firstly, alcohol impairs nervous system cells, causing lightheadedness and delayed reaction times. This effect is compounded when combined with medication, which can also cause drowsiness and dizziness. This combination can be especially harmful to older people, who are more likely to take medication that interacts with alcohol and whose bodies are slower at breaking down alcohol.
Drinking alcohol while taking medication can lead to falls and serious injuries, especially for older people. It can also cause nausea and vomiting, headaches, fainting, loss of coordination, and trouble concentrating or performing mechanical skills. Even small amounts of alcohol can be dangerous when driving, and the combination with medication puts one at an even higher risk.
Furthermore, alcohol can make medication less effective or even harmful to the body. It can put one at risk for internal bleeding, heart problems, and breathing difficulties. It is important to read the label on medication bottles and consult a pharmacist about potential interactions with alcohol.
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Alcohol impairs the immune system
Equate Daytime Cold and Flu is alcohol-free. However, Equate Nighttime Cold and Flu contains 10% alcohol.
Chronic alcohol consumption increases the risk of infections such as pneumonia, HIV, hepatitis C, and tuberculosis. It also impairs responses to vaccinations and exacerbates cancer risk. Alcohol use has been linked to more acute lung disorders such as influenza, pneumonia, and tuberculosis.
Studies in humans have shown that elevated levels of antibodies directed against lipid-peroxidation products are associated with elevated levels of the proinflammatory cytokine tumor necrosis factor-α in the blood. The presence of these antibodies contributes to increased production of inflammatory cytokines, which may have adverse effects.
According to a study in mice, chronic alcohol consumption may impair the ability of lymphocytes to migrate. Lymphocyte migration is essential for the immune system to function properly.
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Frequently asked questions
No, Equate Daytime Cold and Flu is alcohol-free.
Yes, Equate Nighttime Cold and Flu contains 10% alcohol.
No, it is not recommended to consume alcohol with any cold and flu medication, including Equate Nighttime Cold and Flu. Mixing alcohol with this medication can lead to dehydration, nausea, vomiting, headaches, and increased dizziness and drowsiness. It may also impair your immune system and cause severe side effects such as respiratory depression.
The active ingredients in Equate Nighttime Cold and Flu are acetaminophen, dextromethorphan HBr, and doxylamine succinate.
The side effects of Equate Nighttime Cold and Flu may include liver damage, severe skin reactions, and allergic reactions. It is important to carefully read the ingredients and warnings on the packaging and consult a healthcare professional if you have any concerns.




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